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Prof. Thomas Seyfried - 'Cancer as a Metabolic Disease: Implications for Novel Therapies'

Low Carb Down Under · 193.5K views · 2020-09-22 · 44:30

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Overview

A lecture by Prof. Thomas Seyfried arguing that cancer is primarily a metabolic disease rather than a genetic one. It covers the Warburg effect, mitochondrial damage and implications for therapies.

On Hacker News

HN people recommend it for its interesting, if contested, theory of cancer's root cause, noting the content matters more than the delivery.

Recommended by 1 HN people across 4 months · HN mentions 2020–2023

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What people said

LinuxBender · 2022-11 · Recommendation

As does glucose and L-Glutamine. Cancer cells literally live off of glucose, specific amino acids and fermentable fuels. What is the FDA's stance on banning sugar? I would prefer we focus on eliminating molecules from the diet that feed cancer cells and damage mitochondria. I believe we should also cycle up/down molecules that trigger an up-regulation of NRF2/AMPK to literally digest the senescent and especially the damaged cells prior to them becoming cancerous. I am not really a fan of NR/NMN anyway. Both are more expensive than NAM and my body already converts NAM to NR/NMN, it's just a lot slower than superloading NMN directly, not to mention NMN alone will only activate the Sirt genes but other nutrients are required for repair. Excess NMN is converted back to NAM for storage and when there is too much we just urinate it out. But I am no biologist and the folks pushing these supplements will not respond to my inquiries. On a related note take some time to watch a video on Cancer as a metabolic disease. [1] This doctor is not a great speaker but it is the content that matters. [1] - [VIDEO]

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LinuxBender · 2021-12 · Recommendation

There are some other compensating controls that can mitigate cancer but it takes some willpower which I suppose is an entirely different topic all together. This video [1] is worth a watch to learn a bit more about cancer as a metabolic disease. [1] - [VIDEO] [video]

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LinuxBender · 2021-12 · Recommendation

I find this video [1] interesting as it pertains to the root cause of cancer. Compelling theories anyway. [1] - [VIDEO] [video]

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Sources

Video by Low Carb Down Under, played through YouTube.

Data and selection notes

HN summaries and labels may contain AI errors. HN dates refer to discussions, not video publication.

HN Library: HackerTube export (2026-10-31) and open-index/hacker-news. Upstream summaries and classifications may contain AI errors.

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