Original Zoloft Commercial

SuperBowlSammy · 561.7K views · 2009-03-12 · 1:01

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Overview

A one-minute animated commercial for the antidepressant Zoloft, described as the original that inspired later sequels and parodies.

On Hacker News

Mostly cited as a recognizable example of antidepressant advertising in debates about pharmaceutical marketing and the serotonin theory.

Discussed on HN; no positive recommendation is recorded in this export · HN mentions 2019–2025

Topics

Arts & entertainment (other)Medicine & infectious disease Product, marketing & sales

What people said

42772827 · 2025-02 · Criticism
> People who having passing familiarity with neuroscience often assume that psychiatric medications work by correcting deficiencies, but this isn't true. They think this because that’s literally what the commercial for Zoloft said. [0] [0] [VIDEO]
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coding123 · 2022-08 · Criticism
The drug industry does the same thing. Has anyone else watched a anti-depression medicine commercial and suddenly felt they are depressed? [VIDEO] I mean watch this and tell me you don't want what they're selling.
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banads · 2020-01 · Criticism
>Citation required [VIDEO] >"Depression may be related to an imbalance of natural chemicals between nerve cells in the brain. Prescription Zoloft works to correct this imbalance."
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Sources

Video by SuperBowlSammy, played through YouTube.

HN Library · Source license

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HN Library: HackerTube export (2026-10-31) and open-index/hacker-news. Upstream summaries and classifications may contain AI errors.

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