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Evo-Devo (Despacito Biology Parody) | A Capella Science

acapellascience · 6.1M views · 2017-09-23 · 3:53

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Overview

A Capella Science parody of Despacito that sings through evolutionary developmental biology, explaining how a single cell becomes a body, including body-axis genes and dormant snake leg DNA. It runs about four minutes.

On Hacker News

HN recommends it as an entertaining four-minute introduction to evo-devo that works even for people who dislike the original song.

Recommended by 6 HN people across 6 months · HN mentions 2017–2026

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What people said

TeMPOraL · 2025-01 · Recommendation

Yup, DNA turned out to not merely be a sequence of triplets telling a dumb matter printer which hard-coded proteins to make - at least according to what little I understand of evolutionary developmental biology[0], DNA is much more like procedural generation in gamedev or demoscene. That is, there's plenty of recipes for various structures and body parts, and then there's lots of DNA that's responsible for conditionally enabling or disabling or modulating those recipes, depending on more DNA that controls when and where and how much to enable them, and then more - a complex network of logic . -- [0] - Didn't get much further than this four-minute intro to the field, but it is a good intro : [VIDEO] . (EDIT: It's actually the second part of a trio, that starts with a four-minute bottom-up overview of organic chemistry[1], and ends on a three-minute intro to nanotechnology[2]. I recommend the series together for how well it frames humans in relation to other life and universe as a whole.) [1] - [LINK] [2] - [LINK]

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jkingsman · 2024-08 · Recommendation

While this paper is perhaps is a bit of an overfitting of the concept of generative weights, another fun take is Evo-Devo[0], an acapella overview of evolutionary developmental biology. [0]: [VIDEO]

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Terr_ · 2024-06 · Recommendation

Homeobox genes [0] are relevant when it comes to pretty high level "heads go on that end, butts go on that end" stuff. There's also this parody video of Despacito [1] that may be, er, educationally amusing. [0] [LINK] [1] [VIDEO]

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Video by acapellascience, played through YouTube.

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